Updated on August 19, 2025
5 min read

Do Teeth-Whitening Strips Actually Work?

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You’ve probably seen the ads: whitening strips promise to quickly brighten your smile just in time for that upcoming event or photo opportunity. But do these at-home teeth whitening treatments really work—and are they safe for your tooth enamel?

Here’s what research says about their effectiveness, safety, and how to use them wisely compared to professional teeth whitening.

How Do Whitening Strips Work?

Whitening strips are thin polyethylene strips coated with peroxide-based gel designed to lighten teeth by breaking down stains.

Hydrogen peroxide acts faster, typically used at 5 to 15%, while carbamide peroxide (common in professional trays) breaks down more slowly, often overnight.

Strips whiten through peroxide diffusion, reaching beneath enamel surfaces without physically scraping or eroding them. This process oxidizes stain-causing molecules rather than removing enamel.

Common Ingredients in Whitening Strips

The following ingredients are common in tooth whitening strips:

  • Polyethylene ⁠— Most whitening strips are made of polyethylene. It’s one of the most common plastics in the world. Because of its lightweight, flexible, and non-toxic structure, it’s ideal for the base of a whitening strip.
  • Hydrogen or carbamide peroxide ⁠— These are the main active ingredients in whitening strips. They are natural and safe bleaching agents.
  • PVP (polyvinylpyrrolidone) and carbomer ⁠— PVP and carbomer are adhesive agents. They help whitening strips bind to your teeth. Both of these chemicals are safe and non-toxic.
  • Water ⁠— Water is included in the gel to maintain consistency and moisture of the formulation.
  • PEG (polyethylene glycol) ⁠— PEGs are humectants. These are thickeners commonly used in cosmetic products. The PEG acts to thicken the gel and make it sticky.
  • Glycerin ⁠— Glycerin is a sweet, non-toxic compound. It acts as a humectant to thicken the gel and help the strips stay in place.
  • Acrylates copolymer ⁠— Acrylates copolymer is another common ingredient in cosmetic products, including whitening strips. It binds the gel and keeps the strips in one piece.
  • Sodium hydroxide ⁠— Sodium hydroxide is also known as lye or caustic soda. It’s commonly used in whitening strips to adjust the pH to neutral.
  • Sodium saccharin ⁠— Sodium saccharin is an artificial sweetener used to improve the taste.

Get your brightest smile with NewMouth's top teeth whitening picks for 2024.

Do Whitening Strips Actually Work?

Research consistently supports whitening strips as effective for noticeable teeth whitening when used as directed.

Most users achieve at least two to three shades of whitening after one to two weeks of consistent strip use. This level of whitening is comparable to results from professional at-home trays, although usually slower than in-office treatments.

Keep in mind that whitening strips excel at removing surface-level, extrinsic stains caused by coffee, tea, tobacco, and aging. Deeply set intrinsic stains—like tetracycline discoloration—often require prolonged or professionally supervised treatments.

We compared the results of different teeth whitening methods and their treatment duration below:

MethodTypical Shade ImprovementTreatment Duration
OTC Whitening Strips2 to 3 shades1 to 2 weeks
Dentist-Prescribed Trays2 to 4 shades1 to 2 weeks
Professional In-Office4 to 6 shades1 to 2 visits

How Long Do Results Last?

Results typically last several months and can persist up to a few years, depending on individual habits and oral hygiene practices. Periodic maintenance cycles every 6 to 12 months are commonly recommended to sustain brightness.

Prolonged use beyond recommended treatment duration rarely yields significant additional whitening but increases risks like sensitivity.

Are Whitening Strips Safe?

Products that meet American Dental Association (ADA) standards demonstrate proven safety and at least two shades of whitening improvement. Over-the-counter strips usually contain 5 to 15% hydrogen peroxide with recommended wear times of 30 to 60 minutes daily.

Higher concentrations are generally dentist-dispensed or used in-office. In contrast, European regulations strictly limit OTC peroxide levels to just 0.1%, making effective products available only via dental professionals.

Potential Sensitivity and Safety Considerations

Whitening strips are generally safe when used according to instructions, but mild, temporary side effects are common.

  • Dentinal sensitivity ⁠— Up to 50% of users experience some tooth sensitivity during the first few days of treatment. This sensitivity is typically mild and resolves shortly after treatment completion.
  • Gingival irritation ⁠— Poor-fitting strips or gel overflow can irritate gum tissue, causing temporary redness or soreness. Proper application significantly reduces this risk.
  • Enamel myths ⁠— Contrary to popular belief, whitening strips do not erode enamel. They can cause temporary enamel dehydration, leading to transient sensitivity, but saliva quickly rehydrates and remineralizes the enamel surface.
  • Contraindications ⁠— Whitening strips are not recommended during pregnancy, for untreated cavities, or severe fluorosis without dental guidance. If you experience persistent sensitivity or discomfort, discontinue use and consult a dental professional promptly.

How to Choose and Use Strips for Best Results

To maximize your results safely, follow these expert tips:

  • Check the label ⁠— Select products bearing the ADA Seal of Acceptance or those with hydrogen peroxide levels around 10% or less, especially if you're new to whitening.
  • Apply correctly ⁠— Dry your teeth before placing strips to enhance adherence, and avoid swallowing any excess gel.
  • Reduce sensitivity ⁠— Pair whitening treatments with sensitivity-reducing toothpaste containing potassium nitrate or fluoride varnish to minimize discomfort.
  • Watch for red flags ⁠— Uneven whitening or persistent pain are signs you should pause treatment and consult a dental professional.

When is Professional Help a Better Choice?

While whitening strips are convenient, certain situations benefit more from professional dental treatments. For instance, deep, internal stains like those from tetracycline antibiotics typically require prolonged bleaching under professional supervision for best outcomes.

Dental work (e.g., crowns or fillings) that potentially creates uneven coloration won’t be fixed by whitening strips. It’s best to discuss a coordinated cosmetic plan with your dental professional.

If you have sensitive teeth, dentist-supervised custom whitening trays offer lower concentrations of peroxide used over longer periods, significantly reducing sensitivity and gum irritation.

If you're unsure about the best approach for your teeth, we recommend scheduling a quick shade-match consultation. Your dentist can tailor a whitening plan that fits your timeline, budget, and dental health goals.

Last updated on August 19, 2025
7 Sources Cited
Last updated on August 19, 2025
All NewMouth content is medically reviewed and fact-checked by a licensed dentist or orthodontist to ensure the information is factual, current, and relevant.

We have strict sourcing guidelines and only cite from current scientific research, such as scholarly articles, dentistry textbooks, government agencies, and medical journals. This also includes information provided by the American Dental Association (ADA), the American Association of Orthodontics (AAO), and the American Academy of Pediatrics (AAP).
  1. American Dental Association. “Whitening.” American Dental Association, n.d.
  2. Naidu A S, Bennani V, Aarts J M, et al. “Over-the-Counter Tooth Whitening Agents: A Review of Literature.” Brazilian Dental Journal, 2020.
  3. Eachempati P, Kumbargere Nagraj S, Krishanappa S K, et al. “Home-Based Chemically-Induced Whitening (Bleaching) of Teeth in Adults.” Cochrane Database of Systematic Reviews, 2018.
  4. Council of the European Union. “Council Directive 2011/84/EU of 20 September 2011 Amending Council Directive 76/768/EEC Concerning Cosmetic Products.” Official Journal of the European Union, 2011.
  5. FDI World Dental Federation. “Dental Bleaching Materials [Policy Statement].” FDI World Dental Federation, 2018.
  6. Ferrari M, Cagidiaco M C, Monticelli F, et al. “Daytime Use of a Custom Bleaching Tray or Whitening Strips: Initial and Sustained Color Improvement.” American Journal of Dentistry, 2007.
  7. Carvalho T S, Colon P, Ganss C, et al. “Consensus Report of the European Federation of Conservative Dentistry: Erosive Tooth Wear—Diagnosis and Management.” Clinical Oral Investigations, 2015.
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