Product Reviews
Updated on January 25, 2023
11 min read

GLO Teeth Whitening

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GLO Science Teeth Whitening (2023 Review)

GLO Science™ is an award-winning, patented, and FDA-approved LED teeth whitening brand. They are the only at-home teeth whitening system that combines heat and blue LED light to provide faster results without sensitivity.

The GLO Brilliant Teeth Whitening Device is clinically proven to whiten up to five shades lighter in five days. However, everyone is different, and the results depend on your starting shade and lifestyle habits.

Factors that affect the speed of results include:

  • Drinking coffee, tea, wine, or soda
  • Eating acidic food
  • Smoking
GLO Science Teeth Whitening

Quick Overview

If you want to skip the detailed review, you can view and buy GLO’s products here:

How Does GLO Science Teeth Whitening Work?

The GLO Brilliant Kit includes:

  • Vial technology (contains the whitening serum and an easy-to-use brush applicator)
  • An LED Mouthpiece (with blue light LED, heat, and an automatic 8-minute timer)
  • A signature lip treatment (apply pre-application to prevent dryness and irritation on the lips/gums)

Here is an overview of the steps you should follow for the application:

  1. Apply the lip treatment before applying the whitening serum
  2. Twist off the GLO Vial cap and paint a thin gel layer on each tooth
  3. After applying the gel to your front teeth, plug the mouthpiece and place it in your mouth
  4. Reapply the lip treatment as needed throughout the process
  5. After the treatment time is complete (this varies between kits) rinse your mouth and the mouthpiece
  6. Avoid drinking anything for at least 30 minutes
  7. Repeat daily (up to seven days) until you achieve the desired color for your teeth

How Long Does GLO Teeth Whitening Last?

You should use GLO once a month after your first full treatment (five to seven days in a row). You’ll want to perform three or four back-to-back applications to maintain results.

If your teeth discolor quickly, you can perform a full whitening treatment every 4 to 6 months (up to seven consecutive days of whitening).

GLO recommends limiting staining foods/beverages as much as possible to maintain results even longer. These include coffee, red wine, tea, curries, and soda.

How Does LED Teeth Whitening Work?

LED teeth whitening is safe for at-home use. Current research shows that LED whitening is effective when users follow the manufacturer's protocols.

LED as a light source is safer than ultraviolet (UV) light. It speeds up the whitening reaction without leading to risks associated with UV light, like cell mutations and cancer risk.

You’ll apply a bleaching agent to your teeth during the LED whitening process. The LED light activates the whitening agent and starts the chemical reaction. When this reaction occurs, the blue LED light penetrates the enamel and removes stains.

7 Reasons Why You Should Choose GLO

GLO stands out in the LED teeth whitening industry for a few reasons, including:

1. They Offer At-Home and Professional Teeth Whitening Kits

GLO offers both at-home and professional teeth whitening solutions. You can order a kit online and use it in the comfort of your own home. This whitening treatment does not require a prescription or dentist appointment. 

The company also sells GLO Science™ Professional teeth whitening kits to dental practices. These include in-office (chairside) kits, take-home kits, and more. This whitening treatment requires an appointment with a GLO dentist.

2. They Won Two Edison Awards

The GLO Brilliant Teeth Whitening Device has received two prestigious Edison Awards in the “Consumer Packaged Goods” category. They won the silver medal in 2012 and the gold medal in 2013. 

The Edison Awards is an annual competition honoring excellence in new product development. The vision is guided by the legacy of Thomas Edison and his Menlo Park team, who brought remarkable innovations to the market.

3. They Have Patented Products

GLO uses patented G.L.O (Guided Light Optics) Technology. It's used to warm the mouthpiece and whitening gel, speeding up the bleaching process and safely brightening your teeth.

4. They are FDA-Approved 

Unlike many teeth whitening products on the market, GLO Science is FDA-approved. This means the agency has determined that the "benefits of the product outweigh the known risks for the intended use.”

5. The Serum Causes Zero Sensitivity

GLO does not cause sensitivity in the majority of customers. Even if you experience sensitivity, it will likely be very mild and temporary.

GLO’s unique gel formula is carbamide peroxide and alcohol-free, two common causes of tooth sensitivity. The gel is also designed to stay on your teeth and off your gums and soft tissues. This reduces the risk of sensitivity even more.

6. The Kits are Easy-To-Use 

The whitening gel is applied with easy-to-use GLO Vial technology. The whitening process does not require runny gels, trays, or strips.

The G-Vials have a precision brush that allows you to target each tooth (even your back teeth) easily. The brushes also make it easy to avoid your gums and soft tissues. 

7. The Gel is Non-Toxic, Vegan, and Gluten-Free

GLO's whitening gel is made with non-toxic ingredients to provide safe, effective, and cruelty-free whitening. A top aesthetic practicing dentist in New York formulated it.

GLO vs. Other LED Teeth Whitening Brands

GLO AuraGlow Snow
Best for Sensitive Teeth Best Budget Whitening Kit Best-Known Whitening Brand
Cost $199 $80 $149
Free U.S. Shipping
Whitening Time Per Day 32 minutes 30 minutes 21 minutes
# of Treatments Included 10 GLO Vials (40 applications) 20 treatments for 20 days of whitening 75 treatments
Enamel-Safe Ingredients
Heat Whitening Acceleration
Money-Back Guarantee
Hands-Free Mouthpiece
Minimal to No Sensitivity
Lip Treatment Included
Made in the USA
1 Year+ Warranty

GLO Science: Brilliant Collection Review

GLO Brilliant is an innovative and clinically proven teeth whitening device. It combines blue LED light and professional elements of heat. This provides fast, visible results without pain or sensitivity.

What’s Included?

The Glo Brilliant Device includes:

  • Medical-grade LED mouthpiece with heat
  • Mouthpiece case
  • Travel and storage case
  • Blue light remote control 
  • Lanyard (to keep the device in place while multitasking)
  • Lip balm treatment (to apply pre-application)
  • Ten teeth whitening G-Vials (40 applications or 10 days of treatments)
  • Easy user manual with FAQs and detailed instructions 
  • Shade guide
  • Power adapter
  • Universal USB cable  

GLO Brilliant LED Mouthpiece

The patented Glo Mouthpiece is the science behind the brand’s innovation. The mouthpiece combines a safe LED light and warming heat to activate and accelerate the brightening serum on your teeth.

It also has a closed system, preventing oxygen from escaping your teeth. This results in quicker and more effective whitening treatment. 

The mouthpiece is a universal size. It whitens the top and bottom teeth at the same time. 

glo brilliant whitening kit 2 e1673475489536

GLO Brilliant Whitening Gels (GLO Vials)

The patented GLO Vials are used exclusively with GLO teeth whitening systems. The serum contains a glue-like formula that stays in place during the whitening process.

The unique precision brush targets each tooth individually. It also prevents the whitening gel from touching your gums. This helps minimize sensitivity and dryness.

Each GLO vial has enough serum for four applications (one full treatment cycle). The GLO Brilliant kit includes 10 whitening G-Vials, lasting for 40 applications (10 full treatments). 

The whitening gel is vegan, latex/gluten/cruelty-free, and made in the USA. You can buy an extra set of GLO Brilliant Vials to keep your teeth white all year long. 

glo brilliant whitening kit 1 e1673475454286

How to Use the Kit

To use the kit, follow these steps:

  1. Apply a thin layer of the GLO Lip Care to your top and bottom lips. If you have extra sensitive teeth, apply it on the inside of your lips and gum area.
  2. Brush on the whitening gel via the GLO Vial technology. You only need to apply a small bead of gel (1/2 pea-size amount) onto the brush tip applicator. 
  3. Brush a thin gel layer onto your top and bottom teeth (fronts only). 
  4. Put the mouthpiece in and press the GLO button on the remote control. This makes the device light up blue, which means it’s working.
  5. Relax your jaw. You do not need to bite down hard or resist swallowing. The gel will stick to your teeth, so you will not swallow any of it. 
  6. After eight minutes, the mouthpiece will blink and turn itself off.
  7. Remove the mouthpiece and reapply the whitening gel to your teeth. Then place the light back into your mouth for another eight minutes.
  8. Repeat this process every day for five days (or up to 10 days).
  9. After you’ve reached the desired whiteness, only monthly touch-ups are necessary.

Pros of GLO Brilliant

  • Easy-to-use kit with clear directions
  • The serum is easy to apply
  • 8-minute timer and lanyard allow multitasking
  • Mild-tasting serum with a pleasant mint flavor
  • FDA-approved 
  • Won two awards for effectiveness and innovation
  • Comfortable LED mouthpiece that has warming technology to speed up the whitening process
  • Lip treatment included
  • Minimal to no sensitivity 

Cons of GLO Brilliant

  • Reapplication of gel every 8 minutes can be messy
  • Pricey kit

How Much Does GLO Brilliant Cost?

GLO Brilliant costs $149 at full price. You can also select a payment plan through afterpay.

Our Feedback: Before You Buy

One of our writers at NewMouth tried out the GLO Brilliant Whitening Kit for six days. GLO recommends whitening your teeth for five to seven days straight (or up to 10 days). You only have to complete one treatment a day.

Here are things she noticed:

  • It took three uses to see changes in tooth color
  • Her teeth were two to three shades lighter after the sixth treatment day
  • Results faded quickly (upkeep is essential)

After the first full treatment, you should use GLO whitening products once per month, performing three back-to-back applications in one day.

Positive takeaways:

  1. The GLO mouthpiece is comfortable, and the heat feature is a great addition. You can feel the gel warming up on your teeth, and it helps accelerate the whitening process.
  2. The product was packaged well, and the case is perfect for storage and travel. The directions are also easy to follow.
  3. The whitening gel doesn't taste bad (like most whitening gels on the market). It also sticks to your teeth well while in use.
  4. The 8-minute timer and wireless lanyard are convenient. It is easy to know when your whitening session is done because it will blink a few times before turning off.
  5. The whitening gel did not make her teeth sensitive. However, this can vary from person to person.
  6. The product works with consistent use (make sure you read the directions). The whitening results were apparent after two to three uses.
  7. The GLO lip treatment helps keep your lips moist during the whitening process.

Negative takeaways:

  1. The GLO vials can be difficult to apply to your teeth without missing your gums. Thankfully, the gel did not irritate her gums in the process.
  2. It's difficult to use an entire GLO vial during one whitening session. They also expire quickly after being opened, so it's easy to waste some of the gel.
  3. The whitening process is more time-consuming (and messier) than most. It includes four 8-minute applications. However, the comfort of the mouthpiece makes this process easier.
  4. Your lips might dry out if you don't apply the lip treatment after each session.

GLO Teeth Whitening

GLO Brilliant Deluxe Teeth Whitening Device Kit

GLO Science™ is an award-winning, patented, and FDA-approved LED teeth whitening brand. They are the only at-home teeth whitening system that combines heat and blue LED light to give you faster results without sensitivity.

Rating by Alyssa Hill

Overall Value
Ease of Use
Customer Service


Where to Buy GLO Science Teeth Whitening Systems 

The best place to buy GLO Teeth Whitening products is directly from their website. This is because they often have promos and discounts. You cannot get these deals on Amazon. You can also purchase GLO products directly from your dental office.

GLO Science FAQs

What are the ingredients in the GLO whitening gel (G-Vial)?

Ingredients include distilled water, polyethylene glycol, hydrogen peroxide (6%), potassium nitrate, glycerin, edetate disodium, sodium saccharin, sodium fluoride, sodium hydroxide, and flavor.

Are there any add-on treatments for desensitizing? 

No. Since GLO’s unique gel formulation is alcohol-free and carbamide-peroxide-free, sensitivity risks are very low.

Should I brush my teeth before every whitening session?

Yes. You should brush your teeth with toothpaste for two minutes before using GLO.

Can I use GLO with braces or dental restorations (fillings, crowns, etc.)?

GLO is safe for dental restorations, including bonded teeth, porcelain veneers, fillings, crowns, caps, bridges, implants, and others.

Remember: whitening products will not bleach restorations, only untreated teeth. 

GLO whitening cannot be used with braces. Wait until you get them taken off before starting the treatment process. 

How white can my teeth get with GLO?

GLO has been clinically proven to whiten teeth five shades lighter in five days. However, results vary from person to person. 

What is the hydrogen peroxide percentage in the GLO whitening gel?

GLO whitening gel contains 6 percent hydrogen peroxide. 

Should I refrigerate GLO whitening gels?

GLO Vials can be stored at room temperature and do not require refrigeration.

Can I swallow with the gel on my teeth?

Swallow as you usually would while the GLO whitening gel is on your teeth and/or when the mouthpiece is in your mouth. The gel is formulated to stay on your teeth until it evaporates and dissolves.

Why Trust Us?

All medical content on this site, including this guide and other product reviews, is written by our team of experienced writers and researchers. 

All NewMouth writers vet products that are recommended and reviewed in the industry. 

In cases where this is not possible, our team will:

  • Compare positive and negative reviews on the products
  • Talk to company leaders to ensure their products are safe and effective
  • Look into costs to ensure customers are getting the best quality products at reasonable prices
  • Read research studies to compare the pros and cons of each product

Every piece of content is heavily reviewed before publication. All content on NewMouth is also medically reviewed by a licensed dentist, specifically any content where we recommend products. 

Our dentists are specifically instructed to flag any recommendations they don’t agree with. Any products that don’t meet their professional standards are removed.

Last updated on January 25, 2023
7 Sources Cited
Last updated on January 25, 2023
All NewMouth content is medically reviewed and fact-checked by a licensed dentist or orthodontist to ensure the information is factual, current, and relevant.

We have strict sourcing guidelines and only cite from current scientific research, such as scholarly articles, dentistry textbooks, government agencies, and medical journals. This also includes information provided by the American Dental Association (ADA), the American Association of Orthodontics (AAO), and the American Academy of Pediatrics (AAP).
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