Which Brands of Dry Mouth Spray Are Most Effective?
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In this article
What is Dry Mouth Spray?
Dry mouth sprays (saliva substitutes) relieve the symptoms of dry mouth (xerostomia). They incorporate soothing ingredients that can stimulate saliva production.
The spray coats the oral cavity and helps you in:
- Chewing
- Swallowing
- Speaking
- Digesting
It can also rinse away bacteria and protect teeth from cavities. Most sprays are portable and convenient.
How Do Dry Mouth Sprays Work?
Dry mouth sprays coat the oral cavity with a moisturizing agent. You can quickly moisten your mouth with one or two spurts.

Most sprays contain one of the following ingredients:
- Carboxymethylcellulose — Reduces the symptoms of dry mouth by lubricating the oral cavity
- Glycerin — Coats your tongue, teeth, and gums to retain moisture
- Xylitol — Protects your teeth against bacteria and decay
While this product can’t wholly replace normal saliva production, it helps lubricate your tongue, cheeks, gums, and teeth. It can provide dry mouth symptom relief.
This moisturizing mouth spray typically contains a mild mint flavor to make the experience more pleasant. They’re also often alcohol-free to avoid drying out your mouth.
Are Dry Mouth Sprays Safe and Effective?
Dry mouth sprays are safe and effective. You should avoid using them if you are allergic to any ingredient(s).
It’s best to consult your dentist if you’re considering purchasing this mouth spray. Discuss your needs with your primary healthcare provider to avoid medication interactions.
Studies on Using a Moisturizing Mouth Spray
Several studies have shown the effectiveness of dry mouth sprays in providing dry mouth symptom relief.
- Certain dry mouth sprays are more effective than others
- Nearly half of the participants found the dry mouth spray’s taste pleasant
- Dry mouth sprays will not treat the underlying causes of xerostomia
- They’re an effective portable treatment that you can use multiple times daily
While these mouth sprays aren’t a cure or long-term solution, they can immediately relieve xerostomia symptoms.
Can Dry Mouth Sprays Be Used Daily?
You can use dry mouth spray daily as directed by the manufacturer. You can also use the spray to moisten your mouth before bed.
Multiple applications throughout the day are safe. However, do not exceed the recommended dose.
Best Dry Mouth Sprays for Immediate Relief
Below are the top dry mouth spray brands, several of which you can find at your local drugstore or retail center:
| Lubricity Dry Mouth Oral Spray | Essential Sprays Dry Mouth Spray | MouthKote Dry Mouth Spray | **Biotene Moisturizing Spray ** | Pro-Sys Alcohol-Free Dry Mouth Spray | |
|---|---|---|---|---|---|
| **Cost ** | $19.954 | $24.995 | $9.256 | Varies by retailer | $10.498 |
| **Amount ** | 2 fluid ounces | 2 fluid ounces | 2 fluid ounces | 1.5 fluid ounces | 2 fluid ounces |
| **Ingredients ** | Water, xylitol, sodium hyaluronate, sodium benzoate, potassium sorbate | Water, Aloe Barbadensis Leaf Juice, Glycerin, Xylitol, Cocos Nucifera (Coconut) Oil, Mentha Piperita (Peppermint) Oil, Cannabis Sativa (Hemp) Seed Oil., Mentha Arvensis (Menthol), Calcium Ascorbate, Mentha Spicata (Spearmint) Oil | Water, xylitol, sorbitol, Yerba Santa, citric acid, natural lemon-lime flavor, ascorbic acid, sodium benzoate, sodium saccharin | Purified Water, Glycerin, Xylitol, PEG-60, Hydrogenated Castor Oil, VP/VA Copolymer, Flavor, Sodium Benzoate, Xanthan Gum, Methylparaben, Propylparaben, Sodium Saccharin, Cetylpyridinium Chloride | Deionized water, xylitol, glycerin, pluronic, xantham gum, flavor, dimethicone, sodium benzoate, sodium saccharin, EDTA |
| **Flavor ** | Flavorless | Fresh mint | Lemon-lime | Mild mint | Mild mint |
| **Longevity ** | Lasts up to 4 hours | Information unavailable | Lasts for up to 1 hour and 55 minutes | Lasts up to 4 hours | Information unavailable |
| **Sugar content ** | Sugar-free | Sugar-free | Sugar-free | Sugar-free | Sugar-free |
Sugar-free dry mouth sprays help reduce the amount of sugar that sits on your teeth. Look for dry mouth sprays with zero sugar to help maintain your oral health.
How to Use Dry Mouth Sprays
Here are the basic steps involved in using a moisturizing mouth spray:
- Wash your hands and rinse your mouth
- Read the manufacturer’s instructions on priming the spray; you may need to shake or turn the bottle upside down
- Turn the nozzle toward you, close to your lips
- Open your mouth and depress the nozzle to apply the moisturizing mouth spray
- Avoid spraying directly at the back of your throat
- Don’t swallow immediately, but use your tongue to distribute the product
- Reapply the spray as often as directed on the manufacturer’s packaging
Store your spray at room temperature, away from children and pets. Don’t use it if it’s expired; only take the recommended dose per the manufacturer’s label.
Factors to Consider When Purchasing Dry Mouth Spray
With so many dry mouth sprays available, finding the right one can be challenging. Here’s a list of factors to help you decide which dry mouth spray works best for you.
Cost
Most dry mouth sprays cost under $30, but that doesn’t mean they’re a small investment. Depending on how often you use dry mouth spray, you may often need a new bottle, which can increase your costs.
Purchasing a more affordable spray may not offer the best results. So, deciding on the cost can be a balancing act.
Ingredients
Natural dry mouth sprays often prioritize a short list of clean ingredients. If you are allergic to certain ingredients, avoid using sprays that contain them. Many contain xylitol instead of sugar to remain sugar-free.
Ease of Use
The best dry mouth sprays should be easy to use. Depressing the plunger should take little force, and the spray pattern should cover your mouth.
Dry mouth sprays may come with a replaceable cap that protects the nozzle when not in use. Look for a dry mouth spray that doesn’t leak between uses.
Longevity
Most dry mouth sprays can be used multiple times daily, but constantly applying the spray can easily use up the product. Some sprays allow you to go hours between uses, which is convenient. These sprays can also last longer because you don’t need to use so much product.
Tips for Selecting the Best Dry Mouth Spray
Often, the deciding factor between dry mouth sprays is personal preference. Here are a few tips to consider when selecting one for you:
- Look for a mouth spray that’s alcohol-free and contains no artificial sweeteners
- For sensitive teeth and gums, look for a moisturizing mouth spray specifically formulated for your needs
- Search for a mouth spray that contains a pH balance to support natural and healthy bacteria in your mouth
- Select a moisturizing mouth spray based on longevity, ease of use, and taste
- Continue your oral care routine as directed by your dentist while using the mouth spray
You should also consider purchasing a moisturizing mouth spray with the ADA Seal of Acceptance. These products have been shown to combat xerostomia symptoms effectively.
What Users Are Saying About Dry Mouth Sprays
Many people struggle with dry mouth but find dry mouth sprays affordable, effective, and convenient. The application requires little effort, and most sprays allow for several applications within a 24-hour period.
Brands typically offer mild flavors such as mint to avoid a chemical aftertaste. Dry mouth sprays are also discreet and portable, small enough to travel with you through the airport if necessary.
However, some users only found temporary relief with a dry mouth spray. Others reacted adversely to many brands’ flavors, citing them as overwhelming.
A few people also noticed that the spray left a sticky residue in their mouths. Users focused on natural ingredients struggled to find brands offering this product.
What are the Side Effects of Moisturizing Mouth Sprays?
Some dry mouth sprays contain sodium, which can negatively impact your health if you’re on a salt-restricted diet. You may also experience a change in speech with the additional lubricity provided by the dry mouth spray.
If you are allergic to one or more ingredients, you may experience:
- Swelling of the face, lips, tongue, or throat
- Tightness in your chest or throat
- Hives or a skin rash
- Itching
If you experience these symptoms, stop using the mouth spray and seek medical attention immediately.
Summary
Dry mouth sprays are a common, over-the-counter solution for symptoms of xerostomia. These sprays can help relieve dry mouth with several applications throughout the day.
Speak to your dentist or doctor about adding dry mouth spray to your oral care routine. In addition to proper brushing habits, a dry mouth spray can support a healthy mouth.
Sources
- “Xerostomia (Dry Mouth).” American Dental Association, 2023.
- Oh et al. “Effects of carboxymethylcellulose (CMC)-based artificial saliva in patients with xerostomia.” International Journal of Oral & Maxillofacial Surgery, 2008.
- “Dry Mouth.” The American Academy of Oral Medicine, 2023.
- “Lubricity Dry Mouth Oral Spray Full Size.” Lubricity Innovations, 2023.
- “Mouth Kote® Dry Mouth Spray.” Parnell Pharmaceuticals, 2023.
- “Biotène Moisturizing Mouth Spray.” Haleon, 2023.
- “https://www.pro-sys.com/product/dry-mouth-spray/.” Benco Dental, 2023.
- Shirodaria et al. “Subjective assessment of a new moisturizing mouth spray for the symptomatic relief of dry mouth.” The Journal of Clinical Dentistry, 2006.
- Silvestre et al. “Clinical evaluation of a new artificial saliva in spray form for patients with dry mouth.” Medicina oral, patologia oral y cirugia bucal, 2009.
- “Dry Mouth.” MouthHealthy, 2023.
- “Accepted Products.” American Dental Association, 2023.
UCLA-trained dentist practicing in public health. Focuses on whole-body approach to dental care.
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