Updated on February 7, 2024
9 min read

Best Denture Cleaners of 2024

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Cleaning your dentures daily is essential. It increases your dentures’ lifespan, keeps them looking natural, and helps maintain good oral health.

Denture cleansers are products specifically formulated for cleaning dentures, making the process easy and effective. Some require overnight soaking, while others clean dentures in 5 minutes or less.

While you can rinse dentures with water to remove food, warm water alone won’t adequately clean your dental prosthesis. Investing in a denture cleaner is necessary to remove stains, plaque, and calcium deposits.

Best Denture Cleaner

Everything We Recommend

Best Denture Cleaner for Calcium & Calculus Removal: Smile Again Denture Cleaner

Best Denture Cleaning Kit: iSonic Denture Cleaner

Best Cleaner for Partial Dentures: Polident for Partials

Best Denture Cleaner for Stain Removal: ProTech Denture Cleaner

Best Denture Cleaner for Quick Clean: Polident 3 Minute Denture Cleaner

Best On-The-Go Denture Cleaner: Cleanadent Cleansing Wipes

Best Denture Cleaner Paste: Fresh’n Brite Denture Cleaning Paste

Best Overnight Denture Cleaner: Efferdent Overnight Denture Cleanser

8 Best Denture Cleaners

We’ve compiled a list of the best denture cleaners and denture cleanser products to help you decide which option is right for you.

Smile Again Denture Cleaner

Best Denture Cleaner for Calcium & Calculus Removal
Smile Again Denture Cleaner

If you need a cleaning solution to remove tough stains, this one’s for you. Reviewers rave about Smile Again denture cleaner’s ability to remove stains from full or partial dentures. You can use it on other dental appliances, such as retainers and night guards.

Smile Again can remove various stains and deposits, including:

  • Tobacco
  • Tea
  • Fruit
  • Iron
  • Coffee
  • Plaque
  • Calculus
  • Calcium

iSonic Denture Cleaner

Best Denture Cleaning Kit
iSonic Denture Cleaner

The iSonic denture cleaner is the smallest ultrasonic dental appliance cleaner available today. It’s a compact ultrasonic cleaner that uses sound waves to deeply clean dentures. It’s also great for dental appliances like mouthguards and retainers.

The iSonic cleaner comes with a white denture cleaning powder. The powder helps whiten dentures and provides extra cleaning power. You can also just use regular denture cleanser tablets.

Polident for Partials

Best Cleaner for Partial Dentures
Polident for Partials

Partial dentures require a different type of denture cleanser. It’s because they have acrylic and metal in the denture materials.

Polident Partial Denture Cleaner is specially created for partial removable dentures. These antibacterial denture cleanser tablets will kill bacteria while protecting the metal attachments.

ProTech Denture Cleaner

Best Denture Cleaner for Stain Removal
ProTech Denture Cleaner

ProTech is an excellent cleaner for heavily stained dental appliances. The concentrated formula removes stains from all the common culprits, including tea, coffee, iron, and nicotine. 

Reviewers love that ProTech comes as packets of cleaning crystal powder instead of cleaning tablets. What’s better is that each packet will last 7 to 10 days, making this a more economical option than many cleaning tablets.

Polident 3 Minute Denture Cleanser

Best Denture Cleaner for Quick Clean
Polident 3 Minute Denture Cleanser

This is the best denture cleanser for people looking for a quick cleaning solution. Polident 3-Minute denture cleanser tablets remove odor-causing bacteria and tough stains in just a few minutes.

Polident 3-Minute denture cleanser is formulated without abrasive cleaning materials. This means it’s suitable for full or partial dentures and removable orthodontic appliances.

Cleanadent Cleansing Wipes

Best On-The-Go Denture Cleaner
Cleanadent Cleansing Wipes with bg

Cleanadent wipes are perfect for keeping your dentures clean on the go and while traveling. These cleansing wipes are ADA-accepted for effectiveness when used as directed. 

Cleanadent wipes are specially formulated to remove food particles, odor-causing bacteria, and denture adhesive. They also clean your palate and gums while providing extra moisturization for your dentures.

Fresh’n Brite Denture Cleaning Paste

Best Denture Cleaner Paste
Freshn Brite Denture Cleaning Paste

Fresh’n Brite Denture Cleaning Paste is a great alternative to denture soaking solutions. It’s ADA-approved to clean removable dentures, mouth guards, and other dental appliances. 

Fresh’n Brite helps remove stains, plaque, and bacteria from removable dental prostheses.

You can apply Fresh’n Bite to a denture brush or soft toothbrush and use it like regular toothpaste. For best results, use twice daily — in the morning and after meals or before bed.

Efferdent Overnight Denture Cleanser 

Best Overnight Denture Cleaner 
Efferdent Overnight Denture Cleanser

Efferdent Overnight dental appliance cleansing tablets help whiten dentures, clear aligners, and retainers while you sleep. However, these antibacterial denture cleanser tablets only need 3 minutes to kill odor-causing bacteria.

Simply drop a cleansing tablet into enough warm (but not hot) water to cover your dentures. Soak dentures overnight for a deeper clean that brightens your dentures.

How to Clean Your Dentures 

There are many removable denture cleaners available. The cleaning instructions will vary depending on which one you choose.

Here are some tips on how to clean your dentures:

1. Brush Dentures Daily with a Denture Brush 

Daily cleaning with a soft-bristled brush specifically designed for dentures will help remove stubborn stains, food particles, and bacteria.

2. Soak Dentures in a Special Cleanser 

Most denture cleansers contain an antibacterial agent to kill bacteria. This helps remove stains and reduce the risk of oral infections. Remember to follow the product’s instructions when using it.

3. Rinse Dentures After Every Meal 

Rinsing your dentures in warm water will help remove food particles or debris. Don’t use hot water, as that can cause dentures to warp.

4. Clean Your Natural Teeth and Gums 

Brush your teeth and gums with toothpaste and use mouthwash. Keeping your natural teeth and gums healthy is essential to maintain your dentures. It also helps reduce your risk of developing cavities, gum disease, and other dental problems.

5. Avoid Harsh and Abrasive Cleaners 

Stiff-bristled toothbrushes, bleach, and abrasive toothpaste can damage denture teeth. All the denture cleansers on our list are formulated without abrasive cleaning materials.

Handle Dentures Carefully 

Be careful not to drop your dentures while cleaning them, as they can break. Keep a soft towel nearby to catch your denture should it slip out of your hands while cleaning it.

Visit Your Dentist Regularly

Routine dental exams are crucial, especially if you wear dentures. Your dentist can check for any damage or wear and tear on your dentures. They can also detect other oral health issues that may need attention.

What to Consider When Choosing a Denture Cleaner

With so many denture cleansers available, finding the best one for you comes down to personal preference. However, we can help you narrow your options based on your needs.

Here are some things you should consider when choosing a denture cleaner:

Denture Cleaner Type

Only you can decide the best type of denture cleaner for your unique lifestyle. 

Would you rather soak your dentures overnight in a cleaning solution or brush them with a denture paste? Or, you may want to place them in an ultrasonic cleaner.

Trying different products can help determine if you prefer effervescent denture cleaning tablets over cleaning powder. 

Type of Dentures

Full dentures and partial dentures should be cleaned differently. If you have partial dentures, the metal parts need to be cleaned with a separate brush from what you use for your natural teeth.

Additionally, dentures made from flexible acrylic can scratch easily. Avoiding abrasive ingredients is more important when cleaning delicate materials.

Stains on Dentures

Denture stains must be removed carefully to prevent scratches and other damage to your dentures.

Different denture cleansers may better remove certain stains, such as coffee, red wine, or tobacco. Read the package to determine what type of stains a particular denture cleaner targets. 


As mentioned earlier, harsh or abrasive cleaning agents can damage your dentures. In addition to avoiding abrasive materials, check the label for any ingredients you’ve had allergic reactions to.

What If Denture Cleansers Don’t Work?

If you have tried the above products unsuccessfully, visit your dentist. They can help you clean your dentures. 

Your dentist may have special equipment to help remove stains and clean dentures. They may also advise you on effectively cleaning your dentures at home. Tell them what products you tried and describe exactly how you used them.

Why Trust NewMouth?

All medical content on this site, including this guide and other product reviews, is written by our team of experienced writers and researchers. All NewMouth writers vet products that are recommended and reviewed in the industry. 

In cases where this is not possible, our team will:

  • Compare positive and negative reviews on the products
  • Talk to company leaders to ensure their products are safe and effective
  • Look into costs to ensure customers are getting the best quality products at reasonable prices
  • Read research studies to compare the pros and cons of each product

Every piece of content is heavily reviewed before publication. All content on NewMouth is also medically reviewed by a licensed dentist, specifically any content where we recommend products. 

Our dentists are instructed to flag any recommendations they don’t agree with. Any products that don’t meet their professional standards are removed.

Many products we recommend have the American Dental Association (ADA) Seal of Acceptance. These products are proven effective in preventing gum disease, cavities, and other oral health conditions.

We conduct further research to ensure reputability when we recommend products that do not include this seal of acceptance. This may include speaking with company leaders, reading hundreds of customer reviews, and ensuring they provide quality customer service.

Common Questions about Denture Cleaners

What are the benefits of using a denture cleaner?

Denture cleaners ensure you remove all bacteria, plaque, and food particles from dentures. As a result, you’ll have a cleaner set of dentures that will be less likely to irritate your gums. 

Regularly using a denture cleaner helps prevent the buildup of odor-causing bacteria in your mouth.

How often should I use a denture cleaner?

Many denture cleaners should be used twice a day. Read the instructions on the package of your specific denture cleaner to determine how often you should use it.

Are any specific types of denture cleaners better than others?

The type of denture cleaner you should use depends on your dentures and needs. Some denture cleaners are better suited for certain types of dentures. 

Consult with your dentist to determine the best type of denture cleaning product for you.

Can I use a regular toothbrush to clean my dentures?

Using a soft-bristled toothbrush is recommended for cleaning dentures. They’re more gentle on the dentures and will be less likely to cause scratches.


  • It’s important to clean your dentures every day to extend their lifespan and maintain oral health
  • Denture cleaner helps to remove plaque, calcium deposits, and heavy staining
  • The best denture cleaner for you depends on your lifestyle, needs, and budget

Last updated on February 7, 2024
6 Sources Cited
Last updated on February 7, 2024
All NewMouth content is medically reviewed and fact-checked by a licensed dentist or orthodontist to ensure the information is factual, current, and relevant.

We have strict sourcing guidelines and only cite from current scientific research, such as scholarly articles, dentistry textbooks, government agencies, and medical journals. This also includes information provided by the American Dental Association (ADA), the American Association of Orthodontics (AAO), and the American Academy of Pediatrics (AAP).
  1. Cruz et al. “The effectiveness of chemical denture cleansers and ultrasonic device in biofilm removal from complete dentures.” Journal of Applied Oral Science, 2011. 
  2. Mylonas et al. “Denture cleanliness and hygiene: an overview.” British  Dental Journal, 2022.
  3. Duyck et al. “Impact of Denture Cleaning Method and Overnight Storage Condition on Denture Biofilm Mass and Composition: A Cross-Over Randomized Clinical Trial.” PLoS One, 2016.
  4. Axe et al. “Dental health professional recommendation and consumer habits in denture cleansing.” The Journal of Prosthetic Dentistry, 2016.
  5. Gajwani-Jain et al. “Denture Cleansers: A Review.” IOSR Journal of Dental and Medical Sciences, 2015.
  6. Zeynep, Y.D., and Aydiner, S.F. “Evaluation of Methods of Denture Cleaning.” Online Journal of Dentistry & Oral Health, 2021.
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