Product Reviews
Updated on January 22, 2023
6 min read

Best Denture Cleaners of 2023

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8 Best Denture Cleaners of 2023

It is essential to clean your dentures every day.

Not only does it increase your dentures' lifespan and keep them looking natural, but it also helps maintain good oral health.

Cleaning your dentures is easy. Some denture cleaners require overnight soaking, while others clean your dentures in 5 minutes or less.

If you are looking for a deep clean, warm water alone will not be enough to clean your dentures. If the spots are not deep, water can help remove discoloration. However, if you want to remove plaque, calcium deposits, and heavy staining, it is necessary to invest in a denture cleaner.

Everything We Recommend

Best Denture Cleaner for Calcium & Calculus Removal: Smile Again Denture Cleaner

Best Denture Cleaning Kit: iSonic Denture Cleaner

Best Cleaner for Partial Dentures: Polident for Partials

Best Denture Cleaner for Stain Removal: ProTech Denture Cleaner

Best Denture Cleaner for Quick Clean: Polident 3 Minute Denture Cleaner

Best On-The-Go Denture Cleaner: Cleanadent Cleansing Wipes

Best Denture Cleaner Paste: Fresh’n Brite Denture Cleaning Paste

Best Overnight Denture Cleaner: Efferdent Overnight Denture Cleanser

8 Best Denture Cleaners

To help you choose the best denture cleaner for your needs, our specialists at NewMouth have compiled a list of the most popular brands below.

Smile Again Denture Cleaner

Best Denture Cleaner for Calcium & Calculus Removal
Smile Again Denture Cleaner

Smile Again denture cleaner removes stains from full dentures, partial dentures, night guards, and retainers.  

Smile Again can remove tobacco, tea, fruit, iron, coffee, and plaque stains from dentures.

It also claims to remove calculus and calcium from dentures. 

iSonic Denture Cleaner

Best Denture Cleaning Kit
iSonic Denture Cleaner

The iSonic is a compact ultrasonic denture cleaner that uses sound waves to deeply clean dentures, mouth guards, and retainers.

This cleaner also comes with a white denture cleaning powder, which provides extra cleaning power in just five minutes.

It's the smallest ultrasonic denture/retainer cleaner available today.

Polident for Partials

Best Cleaner for Partial Dentures
Polident for Partials

Polident Partial Denture Cleaner is specially created for partial removable dentures.

Partial dentures require a different type of cleaner. They have acrylic and metal in the denture materials adjacent to your natural teeth.

Using this denture cleaner daily will help protect the metal clasps and prevent corrosion.

Using this denture cleaner daily will help protect the metal clasps and prevent corrosion.

ProTech Denture Cleaner

Best Denture Cleaner for Stain Removal
ProTech Denture Cleaner

ProTech is an excellent cleaner for heavily stained dentures. It is capable of removing tea, coffee, iron, and nicotine stains. 

Polident 3 Minute Denture Cleanser

Best Denture Cleaner for Quick Clean
Polident 3 Minute Denture Cleanser

Polident 3 Minute Denture Cleanser is suitable for full/partial dentures, retainers, night guards, and sports mouth guards.

This cleaning solution removes odor-causing bacteria, tough stains, and other bacteria from your dentures in just 3 minutes.

If you have a busy lifestyle and are looking for a quick solution, these Polident denture cleanser tablets are an excellent option.

Cleanadent Cleansing Wipes

Best On-The-Go Denture Cleaner
Cleanadent Cleansing Wipes with bg

The Cleanadent Cleansing Wipes are ADA-approved for effectiveness (when used as directed). 

These wipes are specially formulated to remove food particles, plaque, and denture adhesives. They also clean your palate and gums while providing extra moisturization for your dentures.

Cleanadent wipes are perfect for on the go and while traveling.

Fresh’n Brite Denture Cleaning Paste

Best Denture Cleaner Paste
Freshn Brite Denture Cleaning Paste

Fresh’n Brite Denture Cleaning Paste is ADA-approved for effectiveness (when used as directed). It helps remove stains, plaque, and bacteria from removable dental prostheses.

For best results, you should clean your removable dentures twice daily; in the morning, night, or after eating. You can apply Fresh’n Bite to a denture brush or soft toothbrush. 

Efferdent Overnight Denture Cleanser 

Best Overnight Denture Cleaner 
Efferdent Overnight Denture Cleanser

Efferdent Overnight Denture Cleanser is ADA-approved for effectiveness (when used as directed). These mint anti-bacterial denture cleanser tablets are safe for overnight whitening and soaking. This provides a deeper clean and keeps your dentures bright for many years. 

How to Clean Your Dentures 

There are many removable denture cleaners available. The cleaning instructions will vary depending on which one you choose.

You should clean your dentures every day. This includes:

  • Brushing your dentures daily with a special toothbrush
  • Soaking your dentures in a special cleanser (overnight or according to instructions)
  • Cleaning your teeth and gums with a toothbrush and mouthwash
  • Regular visits to your dentist

Denture wearers should always avoid:

  • Harsh cleaning materials
  • Stiff-bristled toothbrushes
  • Bleach
  • Abrasive toothpaste.

All of these materials will damage your dentures over time. Also, make sure you rinse your denture after cleaning.

Be careful not to drop your dentures while cleaning them, as they can break. Place a towel or sink full of water to catch your denture should it slip out of your hands while cleaning it.

What If These Products Don't Work?

If you have tried the above products unsuccessfully, visit your dentist to see if they can help you clean your dentures. Sometimes the dentist or the laboratory has special equipment to help clean your dentures.

Why Trust NewMouth?

All medical content on this site, including this guide and other product reviews, is written by our team of experienced writers and researchers. All NewMouth writers vet products that are recommended and reviewed in the industry. 

In cases where this is not possible, our team will:

  • Compare positive and negative reviews on the products
  • Talk to company leaders to ensure their products are safe and effective
  • Look into costs to ensure customers are getting the best quality products at reasonable prices
  • Read research studies to compare the pros and cons of each product

Every piece of content is heavily reviewed before publication. All content on NewMouth is also medically reviewed by a licensed dentist, specifically any content where we recommend products. 

Our dentists are instructed to flag any recommendations they don’t agree with. Any products that don’t meet their professional standards are removed.

Many products we recommend have the American Dental Association (ADA) Seal of Acceptance. These products are proven effective in preventing gum disease, cavities, and other oral health conditions.

We conduct further research to ensure reputability when we recommend products that do not include this seal of acceptance. This may include speaking with company leaders, reading hundreds of customer reviews, and ensuring they provide quality customer service.


  • It’s important to clean your dentures every day to extend their lifespan and maintain oral health
  • Denture cleaner helps to remove plaque, calcium deposits, and heavy staining
  • The best denture cleaner for you depends on your lifestyle, needs, and budget
Last updated on January 22, 2023
6 Sources Cited
Last updated on January 22, 2023
All NewMouth content is medically reviewed and fact-checked by a licensed dentist or orthodontist to ensure the information is factual, current, and relevant.

We have strict sourcing guidelines and only cite from current scientific research, such as scholarly articles, dentistry textbooks, government agencies, and medical journals. This also includes information provided by the American Dental Association (ADA), the American Association of Orthodontics (AAO), and the American Academy of Pediatrics (AAP).
  1. Cruz, P., Andrade, et al.. “The effectiveness of chemical denture cleansers and ultrasonic device in biofilm removal from complete dentures.” National Library of Medicine, 2011. 
  2. Mylonas P, et al. “Denture cleanliness and hygiene: an overview.” Br Dent J, 2022.
  3. Duyck J, et al. “Impact of Denture Cleaning Method and Overnight Storage Condition on Denture Biofilm Mass and Composition: A Cross-Over Randomized Clinical Trial.” PLoS One, 2016.
  4. Alyson S., et al. “Dental health professional recommendation and consumer habits in denture cleansing.” The Journal of Prosthetic Dentistry, 2016.
  5. Gajwani-Jain, Shivangi, et al. “Denture Cleansers : A Review.” Pooja Pharane, 2015.
  6. Zeynep Yeşil Duymuş, et al. “Evaluation of Methods of Denture Cleaning.” On J Dent & Oral Health, 2021.
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