Updated on September 24, 2024
6 min read

5 Stages of Cold Sores and What to Do

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Cold sores are a common problem, causing discomfort and sometimes embarrassment. Understanding the different stages of a cold sore can help you manage the symptoms, prevent complications, and minimize the risk of spreading the virus.

In this article, we’ll discuss the five stages of a cold sore and explore what to expect at each phase.

What are the 5 Stages of Cold Sores?

Cold sores are tiny, fluid-filled blisters that usually form on the lips. They are also called fever blisters or oral herpes.

There are 5 distinct stages of a cold sore. However, not everyone experiences the same set of symptoms in the same order.

A cold sore is contagious from the time you first experience symptoms until it’s completely healed. Typical cold sore stages include: 

Stage 1: Tingling 

During this stage, you may feel an odd sensation. A cold sore develops 12 to 24 hours before it’s noticeable. As blisters form, the skin often becomes red, inflamed, and painful. It can also become dry and itchy.

During the first outbreaks, it can take up to 20 days for symptoms to develop after being exposed to the cold sore virus.

Other symptoms include:

  • Burning
  • Tingling with numbness
  • Itching
  • Stinging
  • Throbbing

People who experience these early symptoms of cold sores may never actually have a cold sore outbreak. Applying over-the-counter (OTC) antiviral ointments or prescription antiviral medications may prevent them from forming and improve the healing process.

Stage 2: Blistering

At first, a cold sore blister appears clear, then becomes pus-filled and cloudy. These blisters become painful and redder than usual. The blisters may appear alone or as multiple blisters close together in groups or patches.

Talk to a doctor if a cold sore forms on other parts of your body such as the nose, cheeks, or genitals. You should also talk to a doctor if a cold sore affects your eyes.

Without proper treatment, cold sores that form on or near the eye can lead to an infection which can affect your eyesight. Seek immediate medical attention if the eyes become:

  • Painful
  • Sensitive to light
  • Gritty
  • Runny

Stage 3: Weeping

Cold sore blisters burst and leak, or weep, clear to yellowish-colored fluid for a few days. Sometimes blisters merge before they rupture.

Blisters tend to rupture 2 to 3 days after they develop or 48 hours after warning symptoms develop. Once they rupture, blisters leave behind shallow, red, exposed, and ulcerated sores. The skin around the sores is often painful, dry, and irritated during this period.

Cold sores are most contagious during the weeping stage. Avoid picking or touching weeping sores to prevent them from worsening, spreading, or becoming infected with bacteria.

Stage 4: Crusting

Like other wounds, a cold sore can crust and form scabs after it bursts. Crusting and scabbing typically occur 4 to 5 days after cold sores appear. Scabs may crack or bleed a bit as they heal.

Do not try to pick or pull off scabs or crusting. Applying hydrating creams or ointments can help scabs from becoming too itchy.

Stage 5: Healing

After a few days, the scabs fall or flake off on their own. The skin underneath scabs tends to be redder, pinker, or more sensitive than normal. 

It often takes 1 to 3 weeks for sores to heal completely. If cold sores are recurring, they are often less severe and only take a week to heal.

Most cold sores don’t leave permanent scars unless they’re severe or extensive. However, scabs are often painful and irritating during this stage. 

When Should You See a Doctor?

Most cold sores don’t require medical attention. Talk to a doctor if you have:

  • Cold sores that don’t heal after 2 to 3 weeks
  • An immune condition or weakened immune system
  • Severe symptoms or frequent, large, or numerous cold sores
  • Cold sores on the eyes, genitals, or other body parts
  • A fever, spreading redness, or discolored pus

What Causes a Cold Sore?

Cold sores are contagious and spread through close contact with bodily fluids or secretions. They are most contagious when the blisters are oozing but can spread even when invisible.

The herpes simplex virus 1 (HSV-1) causes most cold sores. But the herpes simplex virus 2 (HSV-2) can also cause it. More than 50% of people in the U.S. have the cold sore virus.

After a cold sore heals, the herpes simplex virus becomes dormant (inactive) and lives in nerve cells. Certain factors can trigger the herpes virus to reactivate and cause sores, which include:

  • Fever and illness
  • Sunlight, wind, and cold weather
  • Stress
  • Immune system changes
  • Injury
  • Fatigue
  • Menstruation and other hormonal fluctuations
  • Dry, damaged, or cracked lips
  • Dental work
  • Cosmetic procedures
  • Gastrointestinal problems

How are Cold Sores Treated? 

A doctor will typically diagnose a cold sore by looking at it. They may also take a swab of the sore and send it away for testing.

Unfortunately, there’s no cure for herpes. However, some medications can help reduce symptoms and speed up healing. 

People with frequent cold sores or a high risk of complications can take antiviral medication routinely or before exposure to triggers. If oral antibiotics are not effective, you can take antiviral medications intravenously (IV). 

Home Remedies For Cold Sores

Some at-home remedies can reduce cold sore symptoms and improve the healing process. At-home remedies for cold sores include:

  • Applying cold compresses
  • Taking oral OTC pain or anti-inflammatory medications, but not aspirin
  • Applying OTC topical treatments with numbing agents with a clean Q-tip or cotton swab
  • Consuming cold, soft foods and drinks
  • Managing stress
  • Applying OTC cold sore patches that protect the skin during healing
  • Drinking plenty of fluids to prevent dehydration
  • Applying zinc ointments or creams to scabs
  • Washing your hands frequently

Things to Avoid When You Have Cold Sores

When you have cold sores, it’s best to avoid eating acidic, salty, or spicy foods. You should also avoid exposing yourself or other people to environmental triggers to prevent contamination. 

You should also avoid sharing utensils and other personal items while you have cold sores. Lastly, avoid touching the sores directly. Use a clean Q-tip or swab if you need to. 

How to Prevent Cold Sores

Some OTC creams and ointments can prevent cold sores if you apply them when you notice early symptoms. You can also take certain steps to reduce the risk of being infected.

There are also ways to prevent cold sores and recurrent outbreaks. Common tips include:

  • Avoid skin-to-skin or intimate contact with someone with cold sores.
  • Wash your hands before touching yourself or others when you have cold sores.
  • Avoid sharing personal items, such as those that touch the skin.
  • Get enough sleep.
  • Protect your skin from harsh sun, wind, or cold.
  • Maintain a healthy, balanced diet.
  • Avoid contact with sick people.

If you experience severe or recurring cold sores, consult with a doctor to discuss potential treatment options and preventive strategies.

Last updated on September 24, 2024
6 Sources Cited
Last updated on September 24, 2024
All NewMouth content is medically reviewed and fact-checked by a licensed dentist or orthodontist to ensure the information is factual, current, and relevant.

We have strict sourcing guidelines and only cite from current scientific research, such as scholarly articles, dentistry textbooks, government agencies, and medical journals. This also includes information provided by the American Dental Association (ADA), the American Association of Orthodontics (AAO), and the American Academy of Pediatrics (AAP).
  1. Cold sores: Overview.” American Academy of Dermatology Association
  2. Cold sores.” Johns Hopkins Medicine.
  3. Cold Sores.” National Health Service, 2024.
  4. Cold sores(HSV-1).” Nemours Teens Health.
  5. Saleh et al. “Herpes Simplex Type 1.” Treasure Island (FL): StatPearls Publishing, 2023.
  6. Overview: Cold sores.” Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG), 2022.
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